Some just have a weird taste but others can change the taste of everything you eat for hours afterword giving things a bitter, metallic taste. ... Don't Know About #1. A lot. Some people notice a diminished sense of taste. Taste changes are especially common among elderly patients who take multiple medications. Some drugs can make food taste different, or they can cause a metallic, salty, or bitter taste in your mouth. My sense of taste always comes back after a week or so. A lost sense of taste is a common symptom, with possible causes ranging from a simple cold to a head injury. Rarely, central neural factors (e.g., tumor or epilepsy) result in loss of taste. 8. I have been on and off this medication over the years since my antidepressants usually stop working after awhile I have to switch. Although captopril is a likely suspect, it is possible that your diuretic may be causing or contributing to the problem. Risk of heart-related effects, muscle rigidity, tremor, seizures, increased sensitivity to light, weight gain or loss, hair loss, skin rash, and edema. Most antidepressants can cause trouble with urination. Viral and bacterial illnesses of the upper respiratory system are a common cause of loss of taste. Methimazole ( Tapazole ) is used to treat hyperthyroidism associated with Graves Disease, and may cause loss of taste due to zinc depletion. The potassium-sparing diuretic amiloride can cause a persistent bitter taste. Taste bud changes can occur naturally as we age or may be caused by an underlying medical condition. You may not taste or smell things the same if you’re hypothyroid. It happens in up to 10% of cases. I also have the side effect of lost sense of taste. Antidepressants don’t make you happy Drugs that Change Taste. Some people call it medicine mouth, the drug companies refer to it as Taste perversion. These are most common in the legs at night, but may affect any part of the body at any time. There are many drugs that cause a change in your sense of taste. Antidepressants are a long-term treatment during which drinking alcohol is not advised. Because diuretics prompt the kidneys to remove water from the body, they can make the mouth dry. Terbinafine may cause loss of taste to the point where it results in weight loss and depression in as many as 3% of folks taking it. All antidepressants can cause twitches or jerky movements (myoclonus) of the head, arms or legs. Alcohol can make depression worse, increase the side effects of antidepressants, counteract the benefits of the medicine, wear down the treatment’s efficacy and, in effect, elongate the treatment time. Learn more about the causes and treatment of a loss of taste here. Thyroid gland problems can range from weight gain to hair loss to depression, but these 7 thyroid symptoms are less recognized and often missed by many doctors. May cause drowsiness and affect a person's ability to drive or operate machinery; some people may develop tolerance to this effect. They then checked how well the volunteers could detect specific "kinds" of taste, and discovered something very interesting indeed: anti-depressants helped taste. I enjoy it while I can because whenever I go back on the zoloft I lose it again. Urinary difficulties.